hrp0092p1-216 | GH and IGFs (1) | ESPE2019

Birth Anthropometry with Cord Blood Insulin-Like Growth Factor 1 and Leptin in Korean Appropriate-For-Gestational-Age Infants Born at ≥28 Weeks' Gestation

Kang Seok Jin , Kim Se Jin , Lee Ga Hyun , Kim Heung Sik

Background: We investigated the relationship of birth anthropometry with cord blood insulin-like growth factor 1 (IGF-1) and leptin levels in Korean infants born at ≥28 weeks' gestation.Methods: One hundred five appropriate-for-gestational-age (AGA) infants, defined as infants with birth weights (BWs) between the 10th and 90th percentiles for gestational age, were enrolled. Enrolled infants were stratified into...

hrp0092p1-217 | GH and IGFs (1) | ESPE2019

Association Between Nonalcoholic Fatty Liver Disease and Growth Hormone Deficiency in Patients with Childhood-Onset Hypopituitarism

Kim Se Jin , Kim Heung Sik , Lee Ga Hyun , Kang Seok Jin

Background & Aims: Although, there has been reports demonstrating association between adult-onset hypopituitarism and development of nonalcoholic fatty liver disease (NAFLD), studies are lacking regarding the development of NAFLD in children and young adult with childhood-onset hypopituitarism. We aimed to identify association between NAFLD and hypopituitarism in these patients.Methods: 76 Korean children and young a...

hrp0092p2-24 | Adrenals and HPA Axis | ESPE2019

Adult Height and Growth Pattern in Patients with Classic Congenital Adrenal Hyperplasia

Lee Ga Hyun , Kim Se Jin , Kang Seok Jin , Kim Heung Sik

Background: Congenital adrenal hyperplasia (CAH), mostly caused by 21-hydroxylase deficiency, is autosomal recessive disorder characterized by impaired cortisol synthesis. It can be presented with a combination of aldosterone and cortisol deficiency and androgen excess. Therefore, excess production of androgen and glucocorticoid replacement can result to early bone maturation and ultimately diminished adult height (AH).Objectives...